BOTICA ESPECIALIZADA EN FÓRMULAS MAGISTRALES
MagneOne
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El tratamiento transdérmico con cloruro de magnesio, permite al magnesio penetrar rápidamente en las células y tiene un fuerte efecto en la bioquímica celular.
El magnesio es necesario para la producción y el almacenamiento de la energía en su totalidad (ATP) y es esencial para mantener normales las funciones muscular y nerviosa
El aceite de magnesio, es la forma más rápida y práctica de que las células y tejidos obtengan altas dosis de magnesio.
Se asimila de inmediato y no tiene el efecto laxante asociado a las formas orales.
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Indicaciones principales :
I ) Alivio del dolor
El aceite de magnesio es especialmente efectivo en el control del dolor. Aplicado en cualquier zona dolorida tiene un efecto casi inmediato en dolores agudos y crónicos
II ) Salud del corazón
El magnesio coordina la actividad del músculo del corazón y es importante en la reducción de la presión sanguínea y del colesterol. Tiene un papel importante en la prevención de la aterosclerosis y la arterioesclerosis y previene los espasmos musculares de los vasos sanguíneos que pueden derivar en un ataque al corazón.
El magnesio también puede mejorar la circulación de la sangre hacia el corazón y descomponer los coágulos de sangre que bloquean las arterias, reducir el deterioro que producen los radicales libres y proteger el músculo del corazón tras un infarto.
III ) Osteoporosis
La suplementación con magnesio mejora la densidad de los huesos y reduce el riesgo de osteoporosis. El magnesio es necesario para activar una enzima necesaria para la formación de los huesos. Estimula la calcitonina .
IV) Estrés, estado de ánimo y sueño
El magnesio disminuye con el estrés físico y psicológico y cuando los niveles de magnesio son bajos se libera más adrenalina con el estrés. Niveles bajos de magnesio pueden llevar a estados de irritabilidad, nerviosismo, agresión y fatiga.
Incluso una deficiencia suave de magnesio causa un déficit de serotonina que conduce a la depresión y trastornos del estado de ánimo.
Mucha evidencia correlaciona los niveles bajos de magnesio con TDAH (Trastorno por Déficit de Atención e Hiperactividad), ansiedad, trastorno bipolar y esquizofrenia.
El magnesio tiene un efecto calmante en el sistema nervioso. Ayuda a promover el sueño y a menudo se descubre su carencia en aquellos que sufren de insomnio.
Mas sobre magnesio
Links
http://www.magnesiumeducation.com
http://www.mgwater.com/
Referencias:
Corazón y valscular
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Pokan, R., P. Hofmann, et al. (2006). "Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients." Br J Sports Med 40(9): 773-8. http://www.ncbi.nlm.nih.gov/pubmed/16825271
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Seelig, M. S. and H. A. Heggtveit (1974). "Magnesium interrelationships in ischemic heart disease: a review." Am J Clin Nutr 27(1): 59-79. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4588182
Shirey, T. L. (2004). "Monitoring magnesium to guide magnesium therapy for heart surgery." J Anesth 18(2): 118-28. http://www.ncbi.nlm.nih.gov/pubmed/15127260
Speziale, G., G. Ruvolo, et al. (2000). "Arrhythmia prophylaxis after coronary artery bypass grafting: regimens of magnesium sulfate administration." Thorac Cardiovasc Surg 48(1): 22-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10757152
Stepura, O. B. and A. I. Martynow (2009). "Magnesium orotate in severe congestive heart failure (MACH)." Int J Cardiol 131(2): 293-5. http://www.ncbi.nlm.nih.gov/pubmed/18281113
Takase, B., T. Akima, et al. (2004). "Effects of chronic sleep deprivation on autonomic activity by examining heart rate variability, plasma catecholamine, and intracellular magnesium levels." Biomed Pharmacother 58 Suppl 1: S35-9. http://www.ncbi.nlm.nih.gov/pubmed/15754837
Ueshima, K. (2005). "Magnesium and ischemic heart disease: a review of epidemiological, experimental, and clinical evidences." Magnes Res 18(4): 275-84. http://www.ncbi.nlm.nih.gov/pubmed/16548143
Vlad, M., G. Uza, et al. (2000). "Magnesium and calcium concentration in the abdominal aorta of patients deceased by ischemic heart disease." Magnes Res 13(1): 37-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10761189
Yokoyama, A., K. Kikuchi, et al. (2005). "[Heart rate variability, arrhythmia and magnesium in hemodialysis patients]." Clin Calcium 15(2): 226-32. http://www.ncbi.nlm.nih.gov/pubmed/15692161
Djurhuus, M. S., J. E. Henriksen, et al. (1999). "Effect of moderate improvement in metabolic control on magnesium and lipid concentrations in patients with type 1 diabetes." Diabetes Care 22(4): 546-54. CONCLUSIONS: Moderate but clinically obtainable improvement of metabolic control in patients with type 1 diabetes seems to reduce the loss of Mg, increase serum HDL cholesterol, and decrease serum triglycerides. The decrease in serum triglycerides was associated with the change in serum total Mg concentration. These reductions in Mg loss and serum triglycerides might reduce the risk of developing cardiovascular disease in patients with type 1 diabetes. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10189530
Published online ahead of print, doi:10.3945/ajcn.112.053132 - American Journal of Clinical Nutrition
“Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies”
Authors: L.C. Del Gobbo, F. Imamura, J.H.Y. Wu, M.C. de Oliveira Otto, S.E. Chiuve, D. Mozaffarian
Altura BM, Altura BT. Influence of magnesium on drug-induced contractions and ion content in rabbit aorta. Am J Physiol 220: 938–944, 1971. [ PubMed] Altura BM, Altura BT. Magnesium and contraction of arterial smooth muscle. Microvascular Res 7: 145–155, 1974. [ PubMed] Altura BM, Altura BT. Magnesium and cardiovascular biology: an important link between cardiovascular risk factors and atherogenesis. Cell Mol Bio Res 41: 347–359, 1995. [ PubMed] Altura BM, Altura BT. Magnesium: forgotten mineral in cardiovascular biology and atherogenesis. In: New Perspectives in Magnesium Research, edited by Nishizawa N, Morii H, Durlach J, editors. New York, NY: Springer, 2007, p. 239–260.
Altura BM, Altura BT, Gebrewold A, Ising H, Gunther T. Magnesium deficiency and hypertension: correlation between magnesium deficient diets and microcirculatory changes in situ. Science 223: 1315–1317, 1984. [ PubMed] Altura BM, Kostellow AB, Zhang A, Li W, Morrill GA, Gupta RK, Altura BT. Expression of the nuclear factor kB and proto-oncogenes c-fos and c-jun are induced by low extracellular Mg2+ in aortic and cerebral vascular smooth muscle cells: possible links to hypertension, atherogenesis and stroke. Am J Hypertens 16: 701–707, 2003. [ PubMed] Altura BM, Shah NC, Jiang XC, Li Z, Perez-Albela JL, Altura BT. Short-term magnesium deficiency results in decreased levels of serum sphingomyelin, lipid peroxidation, and apoptosis in cardiovascular tissues. Am J Physiol Heart Circ Physiol 297: H86–H92, 2009. [ PubMed] Altura BM, Shah NC, Li Z, Jiang XC, Perez-Albela JL, Altura BT. Magnesium deficiency upregulates serine palmitoyl transferase(SPT1 and SPT2) in cardiovascular tissues: relationship to serum ionized Mg and cytochrome c. Am J Physiol Heart Circ Physiol 299: H932–H938, 2010. [ PubMed] Altura BT, Altura BM. Measurement of ionized magnesium in whole blood, plasma and serum with a new ion-selective electrode in healthy and diseased human subjects. Magnesium Trace Elem 10: 90–98, 1991. [ PubMed]
Inflamacion y Dolor
Hypomagnesemia as a possible explanation behind episodes of severe pain in cancer patients receiving palliative care.
López-Saca JM, López-Picazo JM, Larumbe A, Urdíroz J, Centeno C.
Support Care Cancer. 2013 Feb;21(2):649-52. doi: 10.1007/s00520-012-1669-3. Epub 2012 Dec 5.
Crosby V, Elin RJ, Twycross R, Mihalyo M, Wilcock A. J Pain Symptom Manage. 2013 Jan;45(1):137-44. doi: 10.1016/j.jpainsymman.2012.10.005. Epub 2012 Nov 22 Hayward House Macmillan Specialist Palliative Care Unit, Nottingham, United Kingdom.PMID:23182755 [PubMed - in process]
Rayssiguier Y and Mazur A 2005 [Magnesium and inflammation: lessons from animal models]. Clin Calcium 15, 245-248.
Mazur A, Maier J A, Rock E, Gueux E, Nowacki W and Rayssiguier Y 2007 Magnesium and the inflammatory response: potential physiopathological implications. Arch Biochem Biophys 458, 48-56.
Nielsen F H 2010 Magnesium, inflammation, and obesity in chronic disease. Nutr Rev 68, 333-340.
Kim D J, Xun P, Liu K, Loria C, Yokota K, Jacobs D R, Jr. and He K 2010 Magnesium Intake in Relation to Systemic Inflammation, Insulin Resistance, and the Incidence of Diabetes. Diabetes Care.
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Yousef AA, Al-deeb AE.
Anaesthesia. 2013 Mar;68(3):260-6. doi: 10.1111/anae.12107. Epub 2012 Dec 17.
Osteoporosis
Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor-alpha. Rude RK, Gruber HE, Norton HJ, Wei LY, Frausto A, Mills BG. J Nutr. 2004 Jan;134(1):79-85.PMID:14704297[PubMed - indexed for MEDLINE]
Reduction of dietary magnesium by only 50% in the rat disrupts bone and mineral metabolism. Rude RK, Gruber HE, Norton HJ, Wei LY, Frausto A, Kilburn J.Osteoporos Int. 2006;17(7):1022-32. Epub 2006 Apr 7.PMID:16601920 [PubMed - indexed for MEDLINE]
Launius B K, Brown P A, Cush E M and Mancini M C 2004 Osteoporosis: The dynamic relationship between magnesium and bone mineral density in the heart transplant patient. Crit Care Nurs Q 27, 96-100.
Izmozherova N V, Popov A A, Fominykh M I, Andreev A N, Striukova O, Tagil'tseva N V and Gavrilova E I 2007 [Magnesium deficit in climacteric women]. Klin Med (Mosk) 85, 62-64.
Rude R K, Singer F R and Gruber H E 2009 Skeletal and hormonal effects of magnesium deficiency. J Am Coll Nutr 28, 131-141.
Cancer
Rubin H 2005 Central roles of Mg2+ and MgATP2- in the regulation of protein synthesis and cell proliferation: significance for neoplastic transformation. Adv Cancer Res 93, 1-58.
Dai Q, Shrubsole M J, Ness R M, Schlundt D, Cai Q, Smalley W E, Li M, Shyr Y and Zheng W 2007 The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am J Clin Nutr 86, 743-751.
Dai Q and Baron J 2008 “Magnesium, calcium, and colorectal adenoma recurrence: Results from a randomized trial”. Seventh Annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research
Leone N, Courbon D, Ducimetiere P and Zureik M 2006 Zinc, copper, and magnesium and risks for all-cause, cancer, and cardiovascular mortality. Epidemiology 17, 308-314. PMID:16570028
Wolf F I, Cittadini A R and Maier J A 2009 Magnesium and tumors: ally or foe? Cancer Treat Rev 35, 378-382.
Anghileri L J 2009 Magnesium, calcium and cancer. Magnes Res 22, 247-255. J Biol Chem. 2013 January 4; 288(1): 255–263. PMCID: PMC3537020
Rosanoff A 2010 Rising Ca:Mg intake ratio from food in USA Adults: a concern? Magnes Res 23, 181-193.
Piernas inquietas y problems de sueño
Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study.Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D.Sleep. 1998 Aug 1;21(5):501-5.PMID:9703590[PubMed - indexed for MEDLINE]
Nocturnal leg cramps. Allen RE, Kirby KA.Am Fam Physician. 2012 Aug 15;86(4):350-5. Review.PMID:22963024[PubMed - indexed for MEDLINE]
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, Klersy C.J Am Geriatr Soc. 2011 Jan;59(1):82-90. doi: 10.1111/j.1532-5415.2010.03232.x.PMID:21226679 [PubMed - indexed for MEDLINE]
Rapid recovery from major depression using magnesium treatment.Eby GA, Eby KL.Med Hypotheses. 2006;67(2):362-70. Epub 2006 Mar 20.PMID:16542786[PubMed - indexed for MEDLINE]
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